Despite many high profile delays into early 2010, this fall is still chock full of big game releases. What titles are you looking to get, and what titles are you hoping will be good?
Personally, I have to get Assassin's Creed 2 because I absolutely loved the first game. The second one looks to improve upon it, so I have no hesitations about picking it up day one.
Other than that, I'll probably get a couple other games that I am interested in which include Halo: ODST, Modern Warfare 2, Alpha Protocol, Dragon Age: Origins, Brutal Legend, Battlefield: Bad Company 2, and The Saboteur.